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Unexpected Finding of Cerebral Meningioma on 11C-PiB PET

Yamamoto, Yuka MD*; Maeda, Yukito RT*; Kawai, Nobuyuki MD; Kudomi, Nobuyuki PhD; Nishiyama, Yoshihiro MD*

doi: 10.1097/RLU.0b013e3182817c8f
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A 69-year-old man with no history of neurologic or psychiatric disorders underwent 11C-PiB PET as a healthy volunteer for amyloid imaging study. 11C-PiB PET images demonstrated an unexpected increased PiB binding in the left frontal region. MR images demonstrated an extra-axial left frontal mass lesion with mild enhancement, highly suggestive of meningioma. There is a limited amount of published information on the detection of meningioma with 11C-PiB PET.

From the *Departments of Radiology, †Neurosurgery, and ‡Medical Physics, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Received for publication October 25, 2012; and revision accepted November 30, 2012.

Conflicts of interest and sources of funding: none declared.

Reprints: Yuka Yamamoto, MD, Department of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan. E-mail:

© 2013 by Lippincott Williams & Wilkins