Merkel cell carcinoma (MCC) is a rare but very aggressive neuroendocrine tumor of the skin in elderly patients with higher mortality compared with melanoma. No evidence-based standardized chemotherapy exists for metastasized patients.
We report the case of an 87-year-old patient with the history of resection of a large MCC of the parietal scalp planned for radiotherapy and staged with FDG PET/CT showing disseminated distant metastases. 68Ga-DOTATATE PET/CT revealed more extensive tumor load compared with FDG, and due to the intensive expression of somatostatin receptors the patient qualified for 90Y DOTATOC therapy.
From the *Departments of Nuclear Medicine and Radiology, †Oncology, ‡Radiation Oncology, and §Hand and Plastic Surgery, Cantonal Hospital Lucerne, Lucerne, Switzerland.
Received for publication August 21, 2012; and revision accepted November 18, 2012.
Conflicts of interest and sources of funding: none declared.
Reprints: Klaus Strobel, MD, Department of Nuclear Medicine and Radiology, Cantonal Hospital Lucerne, CH 6000 Lucerne 16, Switzerland. E-mail: firstname.lastname@example.org.