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Parathyroid Scintigraphy: When, How, and Why? A Concise Systematic Review

Taieb, David MD*; Hindie, Elif MD; Grassetto, Gaia MD; Colletti, Patrick M. MD§; Rubello, Domenico MD

doi: 10.1097/RLU.0b013e318251e408
Original Articles

In recent years, preoperative imaging has become essential in the evaluation of sporadic primary hyperparathyroidism (HPT) for selecting good candidates for minimally invasive HPT. Its role in patients with secondary/tertiary HPT is under investigation. Imaging is mandatory before reoperative parathyroid surgery for persistent or recurrent HPT, whatever the setting.

This review provides detailed information regarding the nuclear imaging methods (dual phase, subtraction), the role of SPECT and SPECT/CT, and the clinical results of parathyroid scintigraphy in different clinical situations.

From the *Department of Nuclear Medicine, La Timone University Hospital, Aix-Marseille University, Marseille; †Department of Nuclear Medicine, Bordeaux University, Bordeaux, France; ‡Department of Nuclear Medicine, Santa Maria della Misericordia Hospital, Rovigo, Italy; and §Department of Radiology, University of Southern California, Los Angeles, CA.

Received for publication January 11, 2012; revision accepted February 21, 2012.

Conflicts of interest and sources of funding: none declared.

Reprints: Domenico Rubello, Nuclear Medicine, PET Unit, Santa Maria della Misericordia Hospital, Viale Tre Martiri 140, 45100, Rovigo, Italy. E-mail:

© 2012 Lippincott Williams & Wilkins, Inc.