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F-18 FDG PET/CT Imaging and Bronchoscopic Image of Tracheal Recurrence in Patient With Non–Small-Cell Lung Cancer

Oven Ustaalioglu, Bala Basak MD*; Kefeli, Umut MD*; Bilici, Ahmet MD*; Ustaalioglu, Recep MD; Seker, Mesut MD*; Cinaral, Ferahnaz MD; Dogusoy, Ilgaz MD

doi: 10.1097/RLU.0b013e31820aa1c6
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We report tracheal recurrence in patient with non–small-cell lung cancer (NSCLC) who was diagnosed with F-18 fluorodeoxyglucose positron emission tomography/computerized tomography (FDG PET/CT) during follow-up period. A 56-year-old man presented with mediastinum involvement of NSCLC (clinical stage IIIA). After 3 cycles of neoadjuvant platinum-based chemotherapy, he underwent right pneumonectomy. Because tumor in the right main bronchus was located <2 cm distal to the carina, pathologic stage IIB (T3N0M0) disease was diagnosed according to seventh addition of American Joint Committee on Cancer (AJCC) TNM classification. Thereafter, adjuvant 3 cycles of chemotherapy was administered. At the 21st month of follow-up period, he presented with dyspnea and inspiratory stridor. FDG PET/CT was performed and it revealed multiple intense uptake foci in the trachea (SUVmax = 10.1) compatible with malignant tracheal nodules. After rigid bronchoscopy and biopsy were carried out, tracheal recurrence was confirmed. We conclude that it would be interesting to investigate the use of FDG PET/CT in the work-up of tracheal recurrence of NSCLC. Tracheal recurrence was confirmed with rigid bronchoscopy and biopsy.

From the *Department of Medical Oncology, Dr. Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey; †Department of Thoracic Surgery Dr. Siyami Ersek Education and Research Hospital, Istanbul, Turkey; and ‡Department of Nuclear Medicine, Kosuyolu Education and Research Hospital, Istanbul, Turkey.

Received for publication June 9, 2010; revision accepted August 9, 2010.

Reprints: Bala Basak Oven Ustaalioglu, MD, Selimiye Mah, Sair Nesimi Sok, Kardesler Apt. No: 15/2, Daire: 4, 34668, Uskudar, Istanbul, Turkey. E-mail:

© 2011 Lippincott Williams & Wilkins, Inc.