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Inhomogeneous Bone Marrow Uptake Caused by G-CSF Mimics Multiple Bone Metastases on FDG-PET

Nakamoto, Yuji, MD, PhD; Suga, Tsuyoshi, MD; Hara, Tadashi, MD; Ishizu, Koichi, MD, PhD; Togashi, Kaori, MD, PhD

doi: 10.1097/RLU.0b013e3181c7bf4e
Original Article

Administration of granulocyte colony stimulating factor can cause homogeneous hypermetabolic activity of bone marrow in positron emission tomography using F-18-fluorodeoxyglucose. We report a case in which positron emission tomography demonstrated multiple foci of hypermetabolic activity in the bone marrow, which was considered an early effect of granulocyte colony stimulating factor, and not multiple osseous metastases.

From the Department of Diagnostic Radiology, Kyoto University Hospital, Kyoto, Japan.

Received for publication January 15, 2009; revision accepted October 7, 2009.

Reprints: Yuji Nakamoto, MD, PhD, Department of Diagnostic Radiology, Kyoto University Hospital, 54 Shogoinkawahara-cho, Sakyo-ku, Kyoto 606–8507, Japan. E-mail:

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