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Vertebral Body Hemangioma Visualized on Tc-99m HMPAO-Labeled Leukocyte SPECT/CT

Dillman, Jonathan R., MD; Brown, Richard K. J., MD; Frey, Kirk A., MD, PhD; Quint, Douglas J., MD

doi: 10.1097/RLU.0b013e31817debbe
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Tc-99m hexamethylpropyleneamine oxime (HMPAO)-labeled leukocyte scintigraphy is commonly used to evaluate suspected occult acute and chronic pyogenic infectious processes. With the advent of fused single photon emission computed tomography (SPECT)/computed tomography (CT) imaging, areas of scintigraphic abnormality can be immediately and unequivocally anatomically localized. Osteomyelitis of the spine, when present, can demonstrate either focally increased or decreased labeled leukocyte uptake. We present a case of focally decreased labeled leukocyte uptake within the lumbar spine that scintigraphically mimicked osteomyelitis but was determined to represent a vertebral body hemangioma on fused SPECT/CT imaging.

From the Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan.

Received for publication September 9, 2007; revision accepted January 17, 2008.

Reprints: Richard K. J. Brown, MD, Department of Radiology, University of Michigan Health System, B1G505 University Hospital, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0028. E-mail:

© 2008 Lippincott Williams & Wilkins, Inc.