Nonuniformity Artifact Mimicking Extracardiac Uptake on Rubidium-82 Myocardial Perfusion ImageKale, Sameer; Halkar, Raghuveer, MD; Galt, James, PhDClinical Nuclear Medicine: April 2007 - Volume 32 - Issue 4 - p 333-335 doi: 10.1097/01.rlu.0000257287.85352.98 Interesting Image Buy Abstract Author InformationAuthors Article MetricsMetrics Rest and stress rubidium-82 myocardial perfusion imaging is used effectively for assessment of coronary artery disease. Extracardiac uptake of Rb-82 can be seen in the gut, tumors, and vascular structures. However, artifacts caused by improper attenuation or nonuniformity may mimic extracardiac uptake. Here, extracardiac uptake noted in the anterobasal aspect of the heart in oblique slices was due to a nonuniformity artifact caused by failure of a photomultiplier tube as demonstrated in the fused transmission and emission image. It is necessary to check for artifacts when abnormal uptake is seen. Imaging after replacing the photomultiplier tube showed no artifact. From the Radiology Department, Division of Nuclear Medicine and Molecular Imaging, Emory University Hospital, Atlanta, GA. Received for publication July 3, 2006; accepted December 20, 2006. Reprints: R.K. Halkar, MD, Radiology Department, Division of Nuclear Medicine and Molecular Imaging, 1364 Clifton Road NE, Atlanta, GA 30322. E-mail: email@example.com. © 2007 Lippincott Williams & Wilkins, Inc.