Characteristic Appearance on Bone Scintigraphy of a ‘Stone Man’Trikha, Vivek, MBBS, MS*; Kumar, Rakesh, MBBS, MD†; Khan, Shah Alam, MBBS, MS, MRCS*; Rastogi, Shishir, MBBS, MS*Clinical Nuclear Medicine: July 2005 - Volume 30 - Issue 7 - p 517-518 doi: 10.1097/01.rlu.0000167765.07600.5a Interesting Image Buy Abstract Author InformationAuthors Article MetricsMetrics Fibrodysplasia ossificans progressiva (FOP), also known as “stone man disease,” is an extremely rare autosomal dominant disorder. Its incidence is reported to be approximately 1 in 2 million people. The disease is characterized by progressive replacement of fascia, tendons, muscles, and ligaments by bone, leading to encasement of the skeleton within a “new extra skeleton.” It usually appears in the first decade of life, more commonly in males. In the early stages, it may be associated with tender swellings in the muscles. There is no definitive therapy or effective prevention for this condition. We present a case of FOP with its characteristic bone scan appearances. Bone scan helps in the diagnosis of this rare disease, thus protecting the patient from unnecessary biopsies and confusion regarding its diagnosis. From the Departments of *Orthopaedics and †Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India. Received for publication September 15, 2004; accepted November 24, 2004. Reprints: Vivek Trikha, MS, L-381, Sarita Vihar, New Delhi, India. E-mail: email@example.com. © 2005 Lippincott Williams & Wilkins, Inc.