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Hypermetabolism on F-18 FDG PET of Multiple Pulmonary Nodules Resulting From Bronchiolitis Obliterans Organizing Pneumonia

Shin, Lewis MD; Katz, Douglas S. MD; Yung, Elizabeth MD

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There have been multiple reports of benign thoracic conditions demonstrating hypermetabolism on F-18 FDG PET scans, including granulomatous infection, benign tumors, and autoimmune diseases, but bronchiolitis obliterans organizing pneumonia (BOOP) is not a well-known cause of such hypermetabolism. BOOP is an inflammatory lung disease, which may be idiopathic or may be related to prior infection, medications, or connective tissue disorders. Solitary or multiple pulmonary nodules are one of several potential presentations of BOOP. The authors present a case of hypermetabolism on an FDG-PET scan obtained for the evaluation of suspected malignant pulmonary nodules, which proved to be the result of BOOP.

From the Department of Radiology, Winthrop-University Hospital, Mineola, New York.

Received for publication December 17, 2003; accepted January 29, 2004.

Reprints: Douglas S. Katz, Department of Radiology, Winthrop-University Hospital, 259 First Street, Mineola, NY 11501. E-mail:

© 2004 Lippincott Williams & Wilkins, Inc.