Many sarcomas are of intermediate nature, with aggressive local behavior and low-to-moderate tendency to metastasize. A low-grade fibromyxoid sarcoma had abnormal glucose uptake in the principal tumor and contralateral lung metastases with pleural involvement demonstrated with F-18 FDG positron emission tomography (PET). A high-grade malignant hemangiopericytoma had abnormal glucose uptake in the principal tumor and a metastasis in an ipsilateral paratracheal lymph node, but was falsely negative in a small adjacent intraparenchymal lung metastasis. F-18 FDG PET could be useful in rare soft tissue sarcomas to demonstrate sites of possible metastasis and direct biopsy, but is of uncertain negative predictive value with small tumor deposits.
From the *Department of Radiology, Nuclear Medicine Section, the †Department of Medicine, Pulmonary and Critical Care Medicine, the ‡Department of Pathology, Anatomic and Clinical Pathology Sections, the §Department of Medicine, Hematology/Oncology Section, and the ∥Department of Surgery, Cardiothoracic Section, Medical College of Georgia, Augusta, Georgia
Received for publication September 23, 2003; accepted December 21, 2003.
Reprints: Hadyn T. Williams, MD, Associate Professor, Department of Radiology, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912. E-mail: email@example.com