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Reversible Perfusion Disorder on Brain SPECT After Treatment With Prednisone in Temporal Arteritis

DAUTZENBERG, PAUL L.J., M.D.*; LEIJTENS, JAN P.A.M., M.D.

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An 81-year-old woman underwent brain SPECT because of an acute onset of dementia within weeks. Clinically, the dementia was of vascular origin. Contrary to this, the SPECT showed less perfusion in both parietal regions, suggesting Aizheimer disease. Because of a biopsy-proven temporat arteritis, she received corticosteroids and the dementia was partly reversed. After 1 year of treatment, a second SPECT showed the same perfusion disorder on the left side, but also clearly showed a better perfusion on the right side. This finding suggests that SPECT supports clinical improvement of cerebral functions after treatment of temporal arteritis with corticosteroids.

*Department of Geriatrics, Bosch Medicentrum's Hertogenbosch, The Netherlands

Department of Nuclear Medicine, Bosch Medicentrum's Hertogenbosch, The Netherlands

© Lippincott-Raven Publishers.