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Tc-99m MIBI Scintigraphic Detection of Metastatic Insular Thyroid Carcinoma

ZAK, IMAD T., M.D.*; SEABOLD, JAMES E., M.D.*; GURLL, NELSON J., M.D.

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Thallium-201 and, recently, Tc-99m MIBI have been used in conjunction with I-131 scintigraphy for follow-up of patients with well-differentiated thyroid cancer. Insular carcinoma of the thyroid is a fairly aggressive thyroid neoplasm that is believed to arise from follicular cells and usually concentrates I-131. The authors report a patient with recurrent insular thyroid carcinoma in whom bilateral adrenal and lung metastatic lesions developed 3 years after ablative I-131 therapy for cervical lymph node and skeletal metastases. Tc-99m MIBI planar and SPECT images demonstrated these new lesions better than pretherapy I-131 scintigraphy and affords an imaging technique for post-I-131 therapy follow-up that does not require withholding thyroid hormone suppression.

* Departments of Radiology and Surgery, The University of Iowa College of Medicine, Iowa City, Iowa

Departments of Radiology, The University of Iowa College of Medicine, Iowa City, Iowa

© Lippincott-Raven Publishers.