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Hereditary Tyrosinemia

Unusual Imaging Distribution of Gallium-67 Citrate

MALINOFF, HERBERT L., M.D.; MOUNTZ, JAMES M., M.D., PH.D.; WILSON, MARK W., B.S.E.

Clinical Nuclear Medicine: March 1989 - Volume 14 - Issue 3 - p 229
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Gallium-67 citrate (Ga-67) is effective in the imaging of inflammatory processes. During evaluation of an inflammatory process in a patient with hereditary tyrosinemia, an unusual distribution of Ga-67 was observed. The initial and 24-hour delayed images showed intense skeletal uptake with no discemable uptake in the liver or other regions of normal tracer distribution. Our case is unusual because neither the liver function tests nor the hematologic values were grossly abnormal. The case emphasizes that diseases that result in high avidity of Ga-67 to bone may make the diagnosis of an inflammatory process difficult.

From the Department of Internal Medicine, Division of Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan

© Lippincott-Raven Publishers.