Hurd, KA, Surges, MP, and Farrell, JW. Use of exercise training to enhance the power-duration curve: a systematic review. J Strength Cond Res 37(3): 733–744, 2023—The power/velocity-duration curve consists of critical power (CP), the highest work rate at which a metabolic steady state can obtained, and W′ (e.g., W prime), the finite amount of work that can be performed above CP. Significant associations between CP and performance during endurance sports have been reported resulting in CP becoming a primary outcome for enhancement following exercise training interventions. This review evaluated and summarized the effects of different exercise training methodologies for enhancing CP and respective analogs. A systematic review was conducted with the assistance of a university librarian and in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Ten studies met the criteria for inclusion and were reviewed. Four, 2, 2, 1, and 1 articles included swimming, cycling, resistance training, rowing, and running, respectively. Improvements in CP, and respective analogs, were reported in 3 swimming, 2 cycling, and 1 rowing intervention. In addition, only 2 cycling and 1 swimming intervention used CP, and respective analogs, as an index of intensity for prescribing exercise training, with one cycling and one swimming intervention reporting significant improvements in CP. Multiple exercise training modalities can be used to enhance the power/velocity-duration curve. Significant improvements in CP were often reported with no observed improvements in W′ or with slight decreases. Training may need to be periodized in a manner that targets enhancements in either CP or W′ but not simultaneously.