Ghayomzadeh, M, SeyedAlinaghi, S, Shamsi, MM, Rezaei, S, Earnest, CP, Akbarnejad, S, Taj, L, Mohraz, M, Navalta, JW, Ghasemi, P, and Voltarelli, FA. Effect of 8 weeks of hospital-based resistance raining program on TCD4+ cell count and anthropometric characteristic of patients with HIV in Tehran, Iran: A randomized controlled trial. J Strength Cond Res 33(4): 1146–1155, 2019—We examined the effects of an 8-W circuit resistance training (RES) program using elastic bands and body weight on TCD4+ cell counts and anthropometry in patients with HIV. Patients (N = 21) receiving antiretroviral therapy were randomly assigned to resistance training (RES; n = 14) or control (CON; n = 7) groups. RES (3/W) consisted of training with elastic bands and bodyweight training focusing on major muscle groups. CON received standard care. Statistical analyses were performed using general linear models adjusted for age, sex, length of infection, and respective baseline measures. The primary outcome was TCD4+, and secondary outcomes were anthropometry indices. Tertiary assessments explored Pearson correlations surrounding the relationship between changes in anthropometry and TCD4+. We observed significant increases in TCD4+ count accompanying RES training (105.50 cells·mm−3, 95% confidence interval [CI], 47.42–163.59), whereas CON significantly decreased (−41.01 cells·mm−3, 95% CI, −126.78 to 44.76). Significant between-group differences were noted (p < 0.02; n2 = 0.42). We also observed significant reductions in fat mass for RES (1.18 kg, 95% CI = 1.80 to −0.56) vs. increased fat mass for CON (1.21 kg, 95% CI, 0.31 to 2.11). Significant between-group differences were noted (p = 0.001, n2 = 0.64). Similar effects were noted for lean body mass. No significant changes were observed for body mass. Significant correlations were observed for fat mass (r = −0.699, p = 0.001) and lean mass (r = 0.553, p = 0.017), but not body mass (r = −0.390, p = 0.109) vs. changes in TCD4+. Our results suggest that the RES program used in this study is effective for improving TCD4+ status and body composition in patients with HIV.
1Department of Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran;
2Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran;
3Department of Exercise Physiology, Faculty of Sport Science, University of Shahid Beheshti, Tehran, Iran;
4Exercise and Sport Nutrition Laboratory, Texas A&M University, College Station, TX;
5Graduation Program of Physical Education, Faculty of Physical Education, Federal University of Mato Grosso, Cuiabá, Brazil; and
6Department of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, NV
Address correspondence to Minoo Mohraz, email@example.com.