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The Combined Effects of Exercise and Ingestion of a Meal Replacement in Conjunction with a Weight Loss Supplement on Body Composition and Fitness Parameters in College-Aged Men and Women

Poole, Chris N1; Roberts, Michael D2; Dalbo, Vincent J3; Tucker, Patrick S1; Sunderland, Kyle L1; DeBolt, Nick D1; Billbe, Brett W1; Kerksick, Chad M1

The Journal of Strength & Conditioning Research: January 2011 - Volume 25 - Issue 1 - p 51-60
doi: 10.1519/JSC.0b013e3181fee4aa
Original Research

Poole, CN, Roberts, MD, Dalbo, VJ, Tucker, PS, Sunderland, KL, DeBolt, ND, Billbe, BW, and Kerksick, CM. The combined effects of exercise and ingestion of a meal replacement in conjunction with a weight loss supplement on body composition and fitness parameters in college-aged men and women. J Strength Cond Res 25(1): 51-60, 2011-This study was performed to evaluate the combined effect of a meal replacement and an alleged weight loss supplement (WLS) on body composition, fitness parameters, and clinical health in moderately overweight college-aged men and women. Body mass, bench press 1 repetition maximum (1RM), leg press 1RM, body composition, V̇O2max, fasting glucose (GLU), and lipid panels were evaluated before (T1) and after (T2) 8 weeks of combined resistance training (RT) and cardiovascular training (CVT). After T1, subjects were randomly assigned in a double-blind fashion to either the WLS (6 men, 7 women; 21 ± 5 years, 168 ± 8 cm, 75.4 ± 12.7 kg, 31.6 ± 7.7%BFAT) or placebo (PLA: 6 men, 6 women; 22 ± 4 years, 174 ± 9 cm, 84.1 ± 8.8 kg, 30.2 ± 5.6%BFAT) group. Both groups performed 3 d·wk−1 of combined progressive RT (2 × 12 reps of 8 exercises at 75-80% 1RM) and CVT (30 minutes on a cycle ergometer at 70-85% heart rate reserve). Subjects consumed 4 capsules per day and a once-daily meal replacement throughout the protocol. Percent body fat, bench press 1RM, and leg press 1RM significantly improved (p < 0.05) in both groups. Blood GLU (G × T; p = 0.048) improved in WLS and systolic blood pressure (SBP) approached significance (G × T; p = 0.06) in the WLS group. Follow-up analysis of SBP revealed a significant within-group decrease in the WLS group, whereas no within-group changes were found for either group for GLU. Practically speaking, daily supplementation with a meal replacement and a thrice weekly exercise program can increase fitness levels and improve body composition, whereas adding a thermogenic substance provides no additional benefit over fitness or body composition changes but may favorably alter serum markers of clinical health.

1Applied Biochemistry and Molecular Physiology Laboratory, Health and Exercise Science Department, University of Oklahoma, Norman, Oklahoma; 2Department of Biomedical Science, University of Missouri-Columbia, Columbia, Missouri; and 3Institute of Health and Social Science Research, School of Medicine and Applied Sciences, Central Queensland University, Rockhampton, Australia

Address correspondence to Dr. Chad M. Kerksick,

© 2011 National Strength and Conditioning Association