Lack of exercise is related to the development of heart disease, and can also impact other conditions such as obesity, hypertension, hyperlipidemia, atherosclerosis and diabetes. Conversely, understanding the benefits of and engaging in regular physical activity can positively modify these risk factors. The purpose of this study was to examine the effects of a prescribed exercise program implemented in a required university core fitness course on selected student health fitness parameters. One thousand two-hundred and forty-four students originally volunteered to participate in the study. Each student was concurrently enrolled in a content area lecture, and a fitness activity laboratory that convened twice a week. During the initial two weeks of the semester and under laboratory instructor supervision, students were required to complete 8 valid health fitness tests, compile this pre-intervention data on standardized forms and submit them to the instructors. The test items included: resting heart rate and blood pressure, one minute bent-knee sit-ups and push-ups, low back sit and reach flexibility, body composition via 3 site skinfold testing, 8" step test, and a validated cardiorespiratory test, e.g., Rockport/Walkport 1 mile walk, 1.5 mile run, 12 minute run. Over the subsequent 11 weeks, the subjects engaged in personalized activity based interventions that included a variety of cardiorespiratory and resistance training activities, e.g., walking, running, machine aerobics, resistance and flexibility training. During the final two weeks of the semester, post-testing of the original testing items was concluded, compiled on the original forms and returned to the instructors. Four hundred sixty-two students completed all pre and post testing items, and were retained as subjects in the study. Pre/post testing means and standard deviations were calculated as follows: resting heart rate - M = 74.87/71.09, σ = 12.20/11.47; blood pressure - M = 119.19/73.02, 118.53/72.51, σ = 14.93/9.4/ 12.80/ 10.15; bent knee sit-ups - M = 39/42.76, σ = 12.37/14.10; push-ups - M = 30/98/34.76, σ = 13.35/13.03; sit and reach flexibility - M = 13.52/14.35, σ = 3.21/3.30; skinfold body composition - M = 21.28/20.53, σ = 8.83/8.51; 8" step test recovery time - M = 51.82/48.10, σ = 13.36/11.67; cardiorespiratory testing - M = 14.64/14.10, σ = 2.57/3.06. A multivariate within subjects repeated measures design was employed to evaluate the pre and post testing data. Results demonstrated significant gains (p < .001) for all pre-post test dependent variables except for blood pressure (means calculated as acceptable over both tests), and the 8" step test. In general, the activity interventions were mildly effective for this student sample with consideration to the minimum number of days students were required to engage in the prescribed exercise sessions. For future modifications to this study, it is suggested that (1) investigators track and document the actual number of days - minimum or additional, out of class - that students engage in exercise regimens, (2) the course integrate specialty labs, e.g., integrated exercise-weight management, nutrition counseling,10k training, into the laboratory component based on interest and need, and (3) course staff continue to impress on the students the value of regimented, consistent exercise and the importance of tracking personal results.