Resistance training interventions aimed at increasing lower body power and rates of force development have produced varying results. Potentially, the use of WBLFV in between sets of resistance training may increase high-threshold motor unit recruitment and synchronization leading to greater adaptations in both isometric and dynamic performance. The relationship between isometric force/time characteristics and dynamic performance and their respective changes in response to resistance training is of practical importance to strength and conditioning practitioners. To determine the effects of applying whole body vibration prior to and then intermittently between sets of Smith Machine squats upon training induced changes in isometric and dynamic performance and their relationships to one another. Twenty four recreationally resistance trained men were randomly assigned to one of two groups, resistance only (SQT n = 11), or resistance plus whole body vibration (SQTV n = 13). An isometric squat test as well as Squat Jumps (SQJ) and Depth Jumps (DJ) were performed prior to, and following a six-week, periodized Smith Machine squat program. WBLFV was applied 180 s prior to the first work set (50Hz 2-4mm, 30 s) and intermittently (50Hz 4-6mm, 3 × 10 s, 60s between exposures) within a 240s inter-set rest period. Subjects were instructed to assume a quarter squat posture while positioning their feet directly under their center of mass which was modified using a hand held goniometer to a knee angle of 135 ± 5°. Measures of isometric force (N) and isometric rates of force development (N·s−1) were recorded from the onset of contraction (F0) to time points corresponding to F30ms, F80ms, F250ms, Force at initial peak (Finitial), Force at 50% of MVC (MVC50) Time Finitial (ms) as well as the Peak Isometric Force (MVCp) and Peak Isometric Rate of Force Development (PISORFD). Squat jumps were performed with a 20kg Olympic barbell with a linear position transducer attached while the DJ utilized body mass as resistance while dropping from a height of 30cm onto a switch mat. Measures recorded during jumps included jump height (cm) peak power (PMax,W), peak power per kg of body mass (PMax/kg, W/kg) and mean power (Pav,W) for both jump conditions. Correlation matrices matching isometric force/time variables and dynamic (SQJ, DJ) performance within group between weeks 1 and 7(Pre- Post training) revealed multiple significant positive, and negative correlations (p = *<.05 and**<.001, range, r = −.624 to .859). A greater total amount of positive correlations were seen for SQTV (24) compared to SQT (2). Correlation coefficients (r) calculated between percent change (%Δ) scores for similar variables revealed small to moderate r values with the only significant correlation seen for the SQTV group between F30ms and DJ height (cm) (r = −.589, R2 = −.347, p <.05). More positive correlations were seen for isometric and dynamic %Δ variables that for SQTV (9) compared to SQT (7). The addition of WBLFV to the SQTVgroup appeared to effect neuro-muscular training adaptation differently from SQT as reflected in the percent change relationship between isometric and dynamic performance measures following six weeks of exposure. WBLFV may help facilitate early phase adaptations to resistance exercise with a tendency to improve early force time components of isometric and dynamic performance.