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Primary Intracranial Extradural Meningiomas

A Report of 5 Cases and Literature Review

Wang, Hongwei MD; Li, Huqing MD; Wang, Chuanwei MD; Liu, Yuguang MD

doi: 10.1097/WNQ.0000000000000152
Original Articles

Objective: We reviewed 17 cases of primary intracranial extradural meningiomas (PIEMs) (including our 5 cases) reported in the literature so as to develop a better understanding of their clinical characteristics, treatment, and prognosis.

Materials and Methods: The clinical data of 17 cases of PIEMs, including our 5 cases, were analyzed on their demographic features, presenting symptoms and duration, imaging and surgical findings, surgical results, pathologic grades, histologic subtypes, and follow-up results.

Results: PIEMs accounted for 0.04% to 0.14% of all meningiomas. The most common presenting symptom (41.2%) was a painless, gradually expanding mass in the region of the lesion. PIEMs being located in skull convexities constituted 88.2% of all cases, whereas skull bases only 11.8%. All PIEMs patients were uneventful perioperatively after complete resection of tumor except 1 who died of primary cardiac arrest during operation. A total of 88.2% of PIEMs were grade I, 11.8% grade II. Ten cases of PIEMs were given a mean 2.16-year follow-up. As a result, no recurrence and death were found.

Conclusions: PIEMs have some marked clinical characteristics. Total tumor removal together with a wide excision of all involved tissues followed by the reconstruction of tissue defects is the best surgical project. The prognosis is excellent after surgical complete resection.

*Department of Neurosurgery, Qilu Hospital of Shandong University

Brain Science Research Institute of Shandong University, Jinan

Department of Neurosurgery, Gaotang County People’s Hospital of Shandong Province, Liaocheng, P.R. China

The authors declare no conflict of interest.

Reprints: Yuguang Liu, MD, Department of Neurosurgery, Qilu Hospital of Shandong University, No. 107 Wenhua West Road, Jinan 250012, P.R. China (e-mail:

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