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Ventriculitis: A Case of Cerebral Toxoplasmosis in Immunocompetent Child

Azarpira, Negar MD*; Torabineghad, Simin MD*; Rad, Hanieh MD*; Taghipour, Musa MD

doi: 10.1097/WNQ.0b013e31828cc5e1
Case Report
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Cerebral toxoplasmosis is the most important opportunistic infection in patients with acquired immunodeficiency syndrome. However, it is a rare finding in immunocompetent persons. The patient was a 14-year-old boy who presented with headache and vertigo. Toxoplasma serology revealed raised IgG antibody level. No primary or secondary immune deficiency was found. Radiologic examination revealed ventriculitis. Microscopically, the lesion consisted of reactive gliosis and calcification. After antitoxoplasma treatment, the patient condition improved. Brain toxoplasmosis usually presented as periventricular/basal ganglial lesions. We report a case of a child patient with an atypical pattern of toxoplasma encephalitis, presenting with ventriculitis.

Departments of *Pathology

Neurosurgery, Transplant Research Center, Nemazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran

The authors declare no conflict of interest.

Reprints: Negar Azarpira, MD, Department of Pathology, Transplant Research Center, Nemazi Hospital, Shiraz University of Medical Sciences, P.O. Box71935-1119, Shiraz, Iran (e-mail: negarazarpira@yahoo.com).

© 2014 by Lippincott Williams & Wilkins