Original ArticlesSpinal Myxopapillary Ependymoma With Spontaneously Widespread Leptomeningeal Dissemination: A Case ReportFeng, Enshan MD*; Wang, Guihuai MD†; Su, Wei MD†; Yu, Chunjiang MD, PhD*Author Information *Department of Neurosurgery, Sanbo Brain Institute, Fuxing Hospital, Capital Medical University †Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China The authors declare no conflict of interest.Reprints: Chunjiang Yu, MD, PhD, Department of neurosurgery, Fuxing Hospital, Capital University of Medical Sciences, Fu-Xing-Men-Wai Street, Xicheng District, 100038, Beijing, China (e-mail: [email protected]). Neurosurgery Quarterly: August 2011 - Volume 21 - Issue 3 - p 203-206 doi: 10.1097/WNQ.0b013e318213768e Buy Metrics Abstract Myxopapillary ependymomas are low grade tumours that are known to recur locally even after complete excision, but spontaneously widespread dissemination is extremely uncommon. We report the unusual case of a 14-year-old boy suffering from progressive back pain. Magnetic resonance imaging showed spinal lesions associated with intracranial widespread leptomeningeal dissemination. The patient underwent surgical removal of the tumour. Microscopic examination showed histological and immunohistochemical features consistent with a diagnosis of myxopapillary ependymoma. We have performed a careful review of the literature on spinal myxopapillary ependymoma and metastasis. To the best of our knowledge, this present case seems to be the first report on spontaneously widespread leptomeningeal dissemination of a spinal myxopapillary ependymomas without previous surgical intervention. © 2011 Lippincott Williams & Wilkins, Inc.