Article: PDF OnlyTacconi Leonello; Rossif, MarcoNeurosurgery Quarterly: September 1998 - p 191-205 Buy Abstract Summary Choroid plexus papillomas (CPPs) are neuroectodermal neoplasms constituting 0.4% to 0.6% of all central nervous system tumors; 70% to 90% of all CPPs occur in the first 2 years of life. CPPs are usually slow-growing and cause symptoms related to increased intracranial pressure because of concomitant hydrocephalus or focal neurologic signs. Up to 10% of CPPs, however, behave in a clinically malignant fashion or display histologic features of malignancy or, regardless of the latter, feature cerebrospinal fluid dissemination. Elective treatment is radical surgical ablation; radiation therapy and chemotherapy have served only as adjuvants. The authors carried out a comprehensive review of the literature to assess the present state of knowledge with respect to the biology, pathologic diagnosis, modality of treatment, prognosis, and genetics of these neoplasms, with a view to helping the diagnostician and the therapist. © Williams & Wilkins 1998. All Rights Reserved.