CLINICAL NEUROSCIENCE AND NEUROPATHOLOGYHead motion during overt language production in functional magnetic resonance imagingHeim, Stefana b; Amunts, Katrina c; Mohlberg, Hartmuta b; Wilms, Marcusa; Friederici, Angela D.dAuthor Information aResearch Centre Jülich, Institute of Medicine bBrain Imaging Center West (BICW), Jülich cDepartment of Psychiatry and Psychotherapy, RWTH Aachen and dMax Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany Correspondence and requests for reprints to Dr Stefan Heim, Research Centre Jülich, Institute of Medicine, AG Brain Mapping, 52425 Jülich, Germany Tel: +49 2461 61 4208; fax: +49 2461 61 2820; e-mail: [email protected] Sponsorship: Research was supported by the Max Planck Society (SH) and the Human Brain Project/Neuroinformatics research funded by the National Institute of Biomedical Imaging and Bioengineering, the National Institute of Neurological Disorders and Stroke, and the National Institute of Mental Health (K.A.). Received 16 January 2006; accepted 8 February 2006 NeuroReport: April 24, 2006 - Volume 17 - Issue 6 - p 579-582 Buy Abstract Head motion parameters (translation, rotation) during an event-related functional magnetic resonance imaging experiment of overt picture naming were investigated for two fixation conditions. We compared normal fixation with cushions and belts with the additional use of a bite-bar. Neither mean nor maximum values differed between the two conditions for any of the parameters. By applying the head motion parameters to the cytoarchitectonically defined volume of the left Brodmann area 44, we demonstrated volume overlap of 95% (normal fixation) to 100% (bite-bar) that did not differ significantly between fixation conditions. The data encourage further use of overt language production in functional magnetic resonance imaging with careful head fixation but no bite-bar. © 2006 Lippincott Williams & Wilkins, Inc.