VISION, CENTRALSelectivity for speed gradients in human area MT/V5Martinez-Trujillo, Julio C.1 CA; Tsotsos, John K.2 3; Simine, Evgueni2 3; Pomplun, Marc4; Wildes, Richard2 3; Treue, Stefan5; Heinze, Hans-Jochen6; Hopf, Jens-Max6Author Information 1Department of Physiology, McGill University, Montreal, Canada 2Centre for Vision Research, York University, Toronto, Ontario, Canada 3Department of Computer Science York University, Toronto, Ontario, Canada 4Department of Computer Science, University of Massachusetts, Boston, Massachusetts, USA 5Cognitive Neuroscience Laboratory, German Primate Center, Goettingen, Germany 6Department of Neurology II, Otto-von-Guericke University, Magdeburg, Germany CACorresponding Author: [email protected] Received 23 November 2004; accepted 18 January 2005 NeuroReport: April 4, 2005 - Volume 16 - Issue 5 - p 435-438 Buy Abstract Cortical area MT/V5 in the human occipito-temporal cortex is activated by visual motion. In this study, we use functional imaging to demonstrate that a subregion of MT/V5 is more strongly activated by unidirectional motion with speed gradients than by other motion patterns. Our results suggest that like the monkey homolog middle temporal area (MT), human MT/V5 contains neurons selective for the processing of speed gradients. Such neurons may constitute an intermediate stage of processing between neurons selective for the average speed of unidirectional motion and neurons selective for different combinations of speed gradient and different motion directions such as expanding optical flow patterns. © 2005 Lippincott Williams & Wilkins, Inc.