AUDITORY AND VESTIBULAR SYSTEMSPassive music listening spontaneously engages limbic and paralimbic systemsBrown, Steven1 CA; Martinez, Michael J.1 2; Parsons, Lawrence M.1 2Author Information 1Research Imaging Center, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr. MSC 6240, San Antonio, TX 78229-3900, USA 2Present address: Department of Psychology, University of Sheffield, Sheffield, UK CACorresponding Author: [email protected] Received 10 June 2004; accepted 28 June 2004 NeuroReport: September 15th, 2004 - Volume 15 - Issue 13 - p 2033-2037 Buy Abstract In this PET study, non-musicians passively listened to unfamiliar instrumental music revealed afterward to elicit strongly pleasant feelings. Activations were observed in the subcallosal cingulate gyrus, prefrontal anterior cingulate, retrosplenial cortex, hippocampus, anterior insula, and nucleus accumbens. This is the first observation of spontaneous responses in such limbic and paralimbic areas during passive listening to unfamiliar although liked music. Activations were also seen in primary auditory, secondary auditory, and temporal polar areas known to respond to music. Our findings complement neuroimaging studies of aesthetic responses to music that have used stimuli selected by subjects or designed by experimenters. The observed pattern of activity is discussed in terms of a model synthesizing emotional and cognitive responses to music. © 2004 Lippincott Williams & Wilkins, Inc.