Auditory and Vestibular SystemsLayer-specific horizontal propagation of excitation in the auditory cortexKubota, Michinori1,2; Nasu, Masahiro1; Taniguchi, Ikuo1Author Information 1Department of Neurophysiology, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10 Kanda-surugadai, Tokyo 101-0062, Japan 2Corresponding Author: Michinori Kubota ACKNOWLEDGEMENTS: This work was supported by a Grant-in-Aid for Scientific Research (09650457) from the Ministry of Education, Science, Culture, and Sports of Japan and a grant from the Sound Technology Promotion Foundation. Received 6 July 1999; accepted 19 July 1999 NeuroReport: September 9, 1999 - Volume 10 - Issue 13 - p 2865-2867 Buy Abstract OPTICAL imaging was conducted in rat auditory cortex slice preparations to study how horizontal excitation propagates in the cerebral cortex. When a horizontal cut was made between supragranular and infragranular layers, electrical stimulation of layer II/III elicited horizontally propagating excitation in supragranular layers with the same propagating velocities as those seen before a cut was made. Electrical stimulation of layer VI or the border between the white matter and layer VI also elicited horizontally propagating excitation in infragranular layers with the same propagating velocities as those seen before a cut was made. These results suggest that the horizontal propagation of excitation in supragranular and infragranular layers can occur independently in the auditory cortex. © 1999 Lippincott Williams & Wilkins, Inc.