Molecular NeuroscienceBasal forebrain neurons adjacent to the globus pallidus co-express GABAergic and cholinergic marker mRNAsTkatch, Tatiana1; Baranauskas, Gytis1; Surmeier, D. James1,2Author Information 1Department of Anatomy and Neurobiology, College of Medicine, University of Tennessee, 855 Monroe Ave., Memphis, TN 38163, USA. 2Corresponding Author: D. James Surmeier ACKNOWLEDGEMENTS: This work was supported by USPHS NINDS grant NS-26473 to D.J.S. Website publication 20 June 1998 Received 18 March 1998; accepted 5 April 1998 NeuroReport: June 22, 1998 - Volume 9 - Issue 9 - p 1935-1939 Buy Abstract SEMI-QUANTITATIVE single cell RT-PCR techniques were used to determine the expression of mRNAs related to GABAergic and cholinergic neurotransmission in neurons of the rat globus pallidus and adjacent basal forebrain region. Neurons of the globus pallidus expressed relatively high levels of GAD67 and GABA vesicular transporter mRNA but undetectable levels of ChAT or ACh vesicular transporter mRNA. In contrast, nominally basal forebrain neurons co-expressed ChAT and GAD67 mRNAs and mRNAs for both ACh and GABA vesicular transporters. These results suggest that the neurons along the medial border of the globus pallidus may co-release GABA and ACh. © Lippincott-Raven Publishers.