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Mittwoch-Jaffe Tamar; Shalit, Frances; Srendi, Benjamine; Yehuda, Shlomo
NeuroReport: March 27th, 1995
Autonomic Nervous System and Vegetative Control: PDF Only

IN the present study, changes in the cytokine system (IL-1β, IL-2, IL-3, IL-6 and TNFα) were assessed following exposure to mild mood induction (negative and positive) in humans. An increase in secretion of TNFα, a decrease in that of IL-2 and of IL-3 with no change in IL-1β and in IL-6 secretion levels, was observed in response to mild negative emotional changes. A reversed cytokine secretion profile was found following positive mood changes, suggesting the hypothalamic-pituitary- adrenal axis and the autonomic nervous system, as possible mediators underlying these effects, specific to the nature of the emotion.

© 1995 Wolters Kluwer Health | Lippincott Williams & Wilkins