Clinical NeuroscienceStroop N450 reflects both stimulus conflict and response conflictHuang, Bingfang; Chen, CaiqiAuthor Information Center for Studies of Psychological Application and School of Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, South China Normal University, Guangzhou, China Received 27 March 2020 Accepted 8 April 2020 Correspondence to Dr. Caiqi Chen, School of Psychology, South China Normal University, Guangzhou 510631, China, Tel: +020 85216412; e-mail: Chencq@scnu.edu.cn NeuroReport: August 12, 2020 - Volume 31 - Issue 12 - p 851-856 doi: 10.1097/WNR.0000000000001454 Buy Metrics Abstract N450 is described as a valid event-related potential indicator of Stroop interference, but the true specific psychological meaning of the Stroop N450 remains obscure. In the present research, we first used a Chinese character incongruent-eligible task and manipulated different types of conflict to investigate whether Stroop N450 reflects stimulus conflict, response conflict or both. The results showed that, only the N450 in the incongruent-eligible condition was more negative than that of the incongruent-ineligible and neutral conditions in the frontal-central area; simultaneously, there was a left parietal-occipital N450 that successively weakened in the incongruent-eligible, incongruent-ineligible and neutral conditions. These results indicate that Stroop N450 reflects both stimulus conflict and response conflict. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.