BRAIN IMAGINGSpatiotemporal phase-scrambling increases visual cortex activityFraedrich, Eva M.a; Glasauer, Stefana b; Flanagin, Virginia L.a bAuthor Information aGraduate School of Systemic Neurosciences, Ludwig-Maximilians University Munich, Klinikum Groβhadern, Neurological Research Center bBernstein Center for Computational Neuroscience, Ludwig-Maximilians University, Munich, Germany Correspondence to Eva M. Fraedrich, Ludwig-Maximilians University, Klinikum der Universität München, Neurologisches Forschungshaus, Marchioninistrasse 23, 81377 München, Germany Tel: +49 89 7095 7838; fax: +49 89 7095 4801; e-mail: email@example.com Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website (www.neuroreport.com). Received 23 March 2010 accepted 31 March 2010 NeuroReport: June 2nd, 2010 - Volume 21 - Issue 8 - p 596-600 doi: 10.1097/WNR.0b013e32833a7e2f Buy SDC Metrics AbstractIn Brief The hemodynamic response of the visual cortex to continuously moving spatial stimuli of virtual tunnels and phase-scrambled versions thereof was examined using functional magnetic resonance imaging. Earlier functional magnetic resonance imaging studies found either no difference or less early visual cortex (VC) activation when presenting normal versus phase-manipulated static natural images. Here we describe an increase in VC activation while viewing phase-scrambled films compared with normal films, although basic image statistics and average local flow were the same. The normal films, in contrast, resulted in an increased lateral occipital and precuneus activity sparing VC. In summary, our results show that earlier findings for scrambling of static images no longer hold for spatiotemporal stimuli. Supplemental Digital Content is available in the text © 2010 Lippincott Williams & Wilkins, Inc.