COGNITIVE NEUROSCIENCE AND NEUROPSYCHOLOGYOmission mismatch negativity builds up lateHorváth, Jánosa; Müller, Dagmarb; Weise, Annekathrinb; Schröger, Erichb Author Information aInstitute for Psychology, Hungarian Academy of Sciences, Budapest, Hungary bInstitute of Psychology I, University of Leipzig, Leipzig, Germany Correspondence to János Horváth, PhD, Institute for Psychology, Hungarian Academy of Sciences, PO Box 398, Szondi u 83/85, H-1394 Budapest, Hungary Tel: +36 1 354 2397; fax: +36 1 354 2416; e-mail: [email protected] Received 12 February 2010 accepted 7 March 2010 NeuroReport: May 12, 2010 - Volume 21 - Issue 7 - p 537-541 doi: 10.1097/WNR.0b013e3283398094 Buy Metrics Abstract The mismatch negativity (MMN) event-related potential (ERP) is elicited by irregular sounds in a regular sound sequence. MMN depends on the length of the preceding regular stimulation: in repetitive sequences, changes following only two or three repetitions may elicit MMN. Thus, MMN builds up rapidly. Infrequent omissions in a repetitive sound sequence may also elicit an MMN-like waveform. In this study, the build-up of this omission-related ERP was investigated. Trains of two to nine tones with omissions at the penultimate stimulus positions were presented. Results showed no consistent omission-related ERP. In contrast, when omissions occurred with 9% probability among continuously presented tones, the omission-related waveform was elicited. Thus, the omission-related ERP builds up later than MMN. © 2010 Lippincott Williams & Wilkins, Inc.