LEARNING AND MEMORYSubsequent memory-dependent EEG θ correlates to parahippocampal blood oxygenation level-dependent responseSato, Naoyukia b; Ozaki, Takashi J.b; Someya, Yoshiakic d; Anami, Kimitakac e; Ogawa, Seijic f; Mizuhara, Hiroakib g; Yamaguchi, YokobAuthor Information aDepartment of Complex Systems, School of Systems Information Science, Future University–Hakodate, Hakodate, Hokkaido bLaboratory for Dynamics of Emergent Intelligence, RIKEN Brain Science Institute, Wako-shi, Saitama cOgawa Laboratory for Brain Function Res, Hamano Life Science Research Foundation, Tokyo dGlobal COE Program Center for Advanced Research on Logic and Science, Keio University eMusashino Mental Hospital, Saitama fKansei Fukushi Research Center, Touhoku Fukushi University, Sendai gDepartment of Intelligence Science and Technology, Graduate School of Informatics, Kyoto University, Kyoto, Japan Correspondence to Naoyuki Sato, PhD, Department of Complex Systems, School of Systems Information Science, Future University–Hakodate, 116-2 Kamedanakano, Hakodate, Hokkaido 041-8655, Japan Tel: +81 138 34 6235; fax: +81 138 34 6301; e-mail: email@example.com Naoyuki Sato and Takashi J. Ozaki contributed equally to this study Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website (www.neuroreport.com). Received 27 July 2009 accepted 18 August 2009 NeuroReport: February 17th, 2010 - Volume 21 - Issue 3 - p 168-172 doi: 10.1097/WNR.0b013e328332072a Buy SDC Metrics AbstractIn Brief The 4–12 Hz (θ rhythm)-dependent neural dynamics play a fundamental role in the memory formation of the rat hippocampus. Although the power of human scalp electroencephalography θ (EEG θ) is known to be associated with a hippocampus-dependent memory encoding, it remains unclear whether the human hippocampus uses θ rhythm. In this study, we aim to identify the scalp EEG θ-related neural regions during memory encoding by using a simultaneous EEG–functional magnetic resonance imaging recording. We showed that the parahippocampal and the medial frontal and posterior regions were significantly correlated to subsequent memory-dependent EEG θ power. This evidence suggests that the human parahippocampal region and associated structures use θ rhythm during hippocampal memory encoding as in rodents. Supplemental Digital Content is available in the text © 2010 Lippincott Williams & Wilkins, Inc.