BRAIN IMAGINGParietal dysfunction in developmental coordination disorder: a functional MRI studyKashiwagi, Mitsurua c; Iwaki, Sunaod; Narumi, Yoshifumib; Tamai, Hiroshic; Suzuki, Shuheia cAuthor Information Departments of aDevelopmental Brain Science bRadiology cPediatrics, Osaka Medical College dInstitute for Human Science and Biomedical Engineering, National Institute of Advanced, Industrial Science and Technology (AIST), Osaka, Japan Correspondence to Mitsuru Kashiwagi, Department of Developmental Brain Science, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka 569-8686, Japan Tel: +81 72 683 1221; fax: +81 72 684 5798; e-mail: firstname.lastname@example.org Received 31 May 2009 accepted 7 June 2009 NeuroReport: October 7th, 2009 - Volume 20 - Issue 15 - p 1319-1324 doi: 10.1097/WNR.0b013e32832f4d87 Buy SDC Metrics Abstract We aimed to detect the mechanisms underlying clumsiness in children with developmental coordination disorder (DCD). A functional magnetic resonance imaging study of a visuomotor task was performed in 12 boys with DCD and 12 healthy boys (controls) (9–12 years old). They tracked a horizontally moving target by manipulating a joystick. With regard to the behavioural performance, DCD children were significantly less accurate than control children. The comparison of the activation maps showed that the brain activity in the left posterior parietal cortex and left postcentral gyrus was lower in the DCD children than in the control children. These results suggest that the dysfunction of these regions may be the neural underpinnings of impaired motor skill in DCD children. © 2009 Lippincott Williams & Wilkins, Inc.