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Corticospinal tract location in internal capsule of human brain: diffusion tensor tractography and functional MRI study

Kim, Yun-Heea; Kim, Dae-Shikb; Hong, Ji Heone; Park, Chang Hyuna; Hua, Ningc; Bickart, Kevin C.d; Byun, Woo Mokf; Jang, Sung Hog

doi: 10.1097/WNR.0b013e328300a086

We attempted to elucidate the corticospinal tract location at the posterior limb of the internal capsule in the human brain. Ten healthy volunteers were recruited. Probabilistic mapping was performed using the functional MRI activation resulting from a hand motor task as region of interest 1 and the corticospinal tract area of the anterior pons as region of interest 2. The average location of the highest density point of the corticospinal tract was mid-posterior portion with the standard from the most medial point to the most posterior point of the lenticular nucleus. In conclusion, we demonstrated that the corticospinal tract for the hand descended through the posterior portion of the posterior limb at the mid-thalamic level.

aDepartment of Physical Medicine and Rehabilitation, Samsung Medical Center, Sungkyunkwan University School of Medicine

bDepartment of Anatomy and Neurobiology


dDepartment of Anatomy for Biomedical Imaging, School of Medicine Boston University, Massachusetts, USA

eDepartment of Rehabilitation Science, Taegu University

fDepartment of Diagnostic Radiology

gDepartment of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University

Correspondence to Sung Ho Jang, MD, Associate Professor, Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University 317-1, Daemyungdong, Namku, Taegu 705-717, Republic of Korea

Tel: +82 053 620 3269; fax: +82 53 620 3269; e-mail:,

Received 22 January 2008; accepted 11 March 2008

© 2008 Lippincott Williams & Wilkins, Inc.