COGNITIVE NEUROSCIENCE AND NEUROPSYCHOLOGYSex differences in the latency of the late event-related potential mental rotation effectGootjes, Liselotte; Bruggeling, Emma C.; Magnée, Tessa; Van Strien, Jan W.Author Information Institute of Psychology, Faculty of Social Sciences, Erasmus University Rotterdam, Rotterdam, The Netherlands Correspondence to Dr Liselotte Gootjes, PhD, Institute of Psychology, Erasmus University Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands Tel: +31 10 408 8735; fax: +31 10 408 9009; e-mail: email@example.com Received 22 October 2007; accepted 4 December 2007 NeuroReport: February 12th, 2008 - Volume 19 - Issue 3 - p 349-353 doi: 10.1097/WNR.0b013e3282f519b3 Buy Metrics Abstract Sex differences in event-related potentials were examined in 23 women and 24 men during a mental rotation task. We found an early (130–400 ms) and a late (400–700 ms) ERP mental rotation effect. The late rotation effect, which is thought to indicate the onset of the cognitive process of mental rotation, emerged about 100 ms earlier in men than in women. Moreover, men showed about 100 ms shorter response latencies to the task than women. These findings suggest that the faster response in men can be explained as a result of actual mental rotation taking place earlier. Furthermore, we found increased involvement of the right hemisphere specifically in men, probably pointing at a holistic strategy in men during mental rotation. © 2008 Lippincott Williams & Wilkins, Inc.