VISION, CENTRALSpatiotemporal structure of complex cell receptive fields and influence of GABAergic inhibitionLiu, Shenga b; Liu, Yong-Juna; Li, BingaAuthor Information aState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences bGraduate School of the Chinese Academy of Sciences, Beijing, PR China Correspondence to Dr Bing Li, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, PR China Tel: +86 10 6488 8529; fax: +86 10 6485 3625; e-mail: email@example.com Received 15 May 2007; accepted 1 June 2007 NeuroReport: October 8th, 2007 - Volume 18 - Issue 15 - p 1577-1581 doi: 10.1097/WNR.0b013e3282ef8513 Buy Metrics Abstract Spatiotemporal receptive field (RF) profiles were mapped with reverse correlation technique for complex cells in the striate cortex of cat. The RFs were constituted with ON and OFF subfields that overlapped much extensively in space and also largely in time. The subfields had spatial width of 1.0–4.3° and temporal duration of 33–139 ms, whereas late responses were absent in most cases. When microiontophoresis of γ-aminobutyric acid type A (GABAA) antagonist bicuculline was performed on the cells, little change occurred in width and onset time of the subfields, but the duration was prolonged in a subset of cells. These results suggest that intracortical inhibition may contribute to improve the accuracy of visual signals encoded in neuronal activities, but is unlikely critical for determining the primary structure of complex cell RF. © 2007 Lippincott Williams & Wilkins, Inc.