LEARNING AND MEMORYTheta synchronization networks emerge during human object–place memory encodingSato, Naoyuki; Yamaguchi, Yoko Author Information Laboratory for Dynamics of Emergent Intelligence, RIKEN Brain Science Institute, Wako-shi, Saitama, Japan Correspondence to Dr Naoyuki Sato, Laboratory for Dynamics of Emergent Intelligence, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan Tel: +81 48 462 1111(ext7426); fax: +81 48 467 6938; e-mail: [email protected] Received 15 November 2006; accepted 19 December 2006 NeuroReport: March 26, 2007 - Volume 18 - Issue 5 - p 419-424 doi: 10.1097/WNR.0b013e3280586760 Buy Metrics Abstract Recent rodent hippocampus studies have suggested that θ rhythm-dependent neural dynamics (‘θ phase precession’) is essential for an on-line memory formation. A computational study indicated that the phase precession enables a human object–place association memory with voluntary eye movements, although it is still an open question whether the human brain uses the dynamics. Here we elucidated subsequent memory-correlated activities in human scalp electroencephalography in an object–place association memory designed according the former computational study. Our results successfully demonstrated that subsequent memory recall is characterized by an increase in θ power and coherence, and further, that multiple θ synchronization networks emerge. These findings suggest the human θ dynamics in common with rodents in episodic memory formation. © 2007 Lippincott Williams & Wilkins, Inc.