AUDITORY AND VESTIBULAR SYSTEMSGraded cue information in dichotic pitch: effects on event-related potentialsClapp, Wesley C.a b; Johnson, Blake W.a; Hautus, Michael J.a Author Information aResearch Centre for Cognitive Neuroscience, University of Auckland, Auckland, New Zealand bDepartment of Neurology, University of California, San Francisco (UCSF), California, USA Correspondence to Dr Wesley C. Clapp, UCSF MC 2512, Byers Hall Room 1021700, 4th St, San Francisco, CA 94158-2330, USA Tel: +1 6493737599 ext. 84249; fax: +1 64 9 373 7450; e-mail: [email protected] Received 12 October 2006; accepted 25 November 2006 NeuroReport: March 5, 2007 - Volume 18 - Issue 4 - p 365-368 doi: 10.1097/WNR.0b013e32801776d1 Buy Metrics Abstract To determine whether electroencephalogram components elicited by dichotic pitch stimuli are all-or-none threshold-like responses or graded responses that depend on the saliency of the stimuli, we recorded electroencephalograms while participants listened to dichotic pitch stimuli constructed with different signal-to-background ratios. The object-related negativity and P400 components were largest when the dichotic pitch was most salient (high signal-to-background ratio), and decreased in amplitude with decreasing signal-to-background ratio. These results are similar to those reported for mistuned harmonics, thereby providing additional evidence that the object-related negativity and P400 components observed for these disparate stimulus types reflect similar processing. They also support the notion that the object-related negativity and P400 amplitudes are dependent on the level of relevant cue-based stimulus information. © 2007 Lippincott Williams & Wilkins, Inc.