AUDITORY AND VESTIBULAR SYSTEMSA role for the inferior colliculus in multisensory speech integrationChampoux, Françoisa; Tremblay, Corinneb c; Mercier, Claudec; Lassonde, Maryseb c; Lepore, Francob c; Gagné, Jean-Pierrea; Théoret, Hugob cAuthor Information aSchool of Audiology and Speech Language Pathology bDepartment of Psychology, University of Montreal cSainte-Justine Hospital Research Center, Quebec, Canada Correspondence and requests for reprints to Dr Hugo Théoret, PhD, Département de Psychologie, Pavillon Marie-Victorin, 90 Vincent d'Indy, Québec, Canada H2 V 2S9 Tel: +1 514 343 6362; fax: +1 514 343 5787; e-mail: [email protected] Sponsorship: This work was supported by grants from CIHR, FRSQ and NSERC. Received 6 July 2006; accepted 11 July 2006 NeuroReport: October 23, 2006 - Volume 17 - Issue 15 - p 1607-1610 doi: 10.1097/01.wnr.0000236856.93586.94 Buy Metrics Abstract Multisensory integration can occur at relatively low levels within the central nervous system. Recent evidence suggests that multisensory audio-visual integration for speech may have a subcortical component, as acoustic processing in the human brainstem is influenced by lipreading during speech perception. Here, stimuli depicting the McGurk illusion (a demonstration of auditory–visual integration using speech stimuli) were presented to a 12-year-old child (FX) with a circumscribed unilateral lesion of the right inferior colliculus. When McGurk-type stimuli were presented in the contralesional hemifield, illusory perception reflecting bimodal integration was significantly reduced compared with the ipsilesional hemifield and a group of age-matched controls. These data suggest a functional role for the inferior colliculus in the audio-visual integration of speech stimuli. © 2006 Lippincott Williams & Wilkins, Inc.