AUDITORY AND VESTIBULAR SYSTEMSEffects of the frequency of interaural time difference in the human brainSoeta, Yoshiharu; Nakagawa, Seiji Author Information Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan Correspondence and requests for reprints to Yoshiharu Soeta, Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Midorigaoka, Ikeda, Osaka 563-8577, Japan Tel: +81 72 751 9496; fax: +81 72 751 8416; e-mail: [email protected] Received 27 December 2005; accepted 23 January 2006 NeuroReport: April 3, 2006 - Volume 17 - Issue 5 - p 505-509 doi: 10.1097/01.wnr.0000208998.31072.e4 Buy Metrics Abstract The two cues to the horizontal location sound sources are interaural time differences and interaural level differences. For low-frequency tones, interaural time differences provide effective and unambiguous information. For higher frequency sounds, however, interaural time differences provide ambiguous cues. In order to evaluate the effect of frequency of interaural time differences in the human auditory cortex, the auditory evoked fields to different interaural time differences of pure tone were examined. The results showed that the N1m magnitudes varied with the interaural time differences when the frequency of the pure tone was 800 Hz. The N1m magnitudes, however, did not vary with the interaural time differences when the frequency of the pure tone was 1600 Hz. These results indicate that localization performance might be reflected in N1m magnitudes. © 2006 Lippincott Williams & Wilkins, Inc.