AUDITORY AND VESTIBULAR SYSTEMSEffects of prosodic emotional intensity on activation of associative auditory cortexEthofer, Thomasa b; Anders, Silkea b; Wiethoff, Saraha b; Erb, Michaela; Herbert, Corneliac; Saur, Ralfa; Grodd, Wolfganga; Wildgruber, DirkbAuthor Information aSection of Experimental MR of the CNS, Department of Neuroradiology bDepartment of Psychiatry, University of Tuebingen, Tuebingen and cDepartment of Psychology, University of Konstanz, Konstanz, Germany Correspondence and requests for reprints to Thomas Ethofer, MD, Section of Experimental MR of the CNS, Department of Neuroradiology, Otfried-Mueller-Strasse 51, University of Tuebingen, 72076 Tuebingen, Germany Tel: +49 7071 2987385; fax: +49 7071 294371; e-mail: Thomas.Ethofer@med.uni-tuebingen.de Sponsorship: This study was supported by the Deutsche Forschungsgemeinschaft (DFG grant WI 2101/1–2) and by the Junior Science Program of the Heidelberger Academy of Sciences and Humanities. Received 3 December 2005; accepted 12 December 2005 NeuroReport: February 27th, 2006 - Volume 17 - Issue 3 - p 249-253 doi: 10.1097/01.wnr.0000199466.32036.5d Buy Metrics Abstract Functional magnetic resonance imaging was used to investigate hemodynamic responses to adjectives pronounced in happy and angry intonations of varying emotional intensity. In separate sessions, participants judged the emotional valence of either intonation or semantics. To disentangle effects of emotional prosodic intensity from confounding acoustic parameters, mean and variability of volume and fundamental frequency of each stimulus were included as nuisance variables in the statistical models. A linear dependency between hemodynamic responses and emotional intensity of happy and angry intonations was found in the bilateral superior temporal sulcus during both tasks, indicating that increases of hemodynamic responses in this region are elicited by both positive and negative prosody independent of low-level acoustic properties and task instructions. © 2006 Lippincott Williams & Wilkins, Inc.