VISION, RETINAVoltage-gated K+channel subunits on cholinergic and dopaminergic amacrine cellsTian, Miao1 2; Zhao, Jing-Wei1; Yang, Xiong-Li1 CA; Xie, Jun-Xia2 Author Information 1Institute of Neurobiology, Fudan University, 220 Han-Dan Road, Shanghai 200433 2Department of Physiology, Qingdao University Medical College, 38 Deng-Zhou Road, Qingdao 266021, PR China CACorresponding Author: [email protected] Received 4 June 2003; accepted 8 June 2003 NeuroReport: October 6, 2003 - Volume 14 - Issue 14 - p 1763-1766 Buy Abstract The expression of voltage-gated K+ (Kv) channel subunits on rat retinal cholinergic and dopaminergic amacrine cells was studied using double immunofluorescence labeling and confocal laser scanning microscopy. Staining for Kv3.1b was found in the cholinergic cells, being present on the membrane of somata, and on the processes, but not in the dopaminergic cells. Kv4.3-immunoreactivity was localized on the somatodendritic compartment of the dopaminergic cells, but was not found in the cholinergic cells. Differential expression between the two cell types was not found for 10 other subunits tested. These results suggest that the Kv3.1b and Kv4.3 subunits may differentially contribute to the electrophysiological properties underlying distinct functions of these two retinal interneurons. © 2003 Lippincott Williams & Wilkins, Inc.