ArticlesCortical reorganization associated with motor recovery in hemiparetic stroke patientsJang, Sung Ho; Kim, Yun-Hee1; Cho, Sang-Hyun2,CA; Chang, Yongmin3; Lee, Zee In4; Ha, Jung Sang5 Author Information Department of Physical Medicine and Rehabilitation; 5Department of Neurology, School of Medicine, Yeungnam University, 317–1, Daemyung-dong, Nam-ku, Taegu, 705–717; 1Department of Physical Medicine and Rehabilitation, School of Medicine, Sungkyunkwan University, Samsung Medical Center, 50 Ilwon-dong, Kangnam-ku, Seoul, 135–710; 2Department of Physical Therapy, Yonsei University College of Health Science, Wonju-si, Kangwon-do, 220–710; 3Department of Diagnostic Radiology, College of Medicine Kyungbook National University, 2288 Samduk-dong, Jung-ku, Daegu, 750–030; 4Department of Physical Medicine and Rehabilitation, School of Medicine, Taegu Catholic University, 3046–6 Daemyung-dong, Nam-ku, Taegu, 705–718, Republic of Korea CACorresponding Author: [email protected] Received 2 February 2003; accepted 24 March 2003 NeuroReport 14(10):p 1305-1310, July 18, 2003. | DOI: 10.1097/01.wnr.0000078700.79393.09 Buy Metrics Abstract We investigated the cortical activation changes associated with motor recovery in eight hemiparetic patients with cerebral infarct by using functional MRI (fMRI), which was performed at 1.5T in parallel with finger flexion-extension movements at a fixed rate. The first fMRI was performed when the patient was able to flex and extend fingers of the affected hand against gravity, and the second fMRI was done when the motor function of the affected hand showed definite improvement. The main cortical activation changes that occurred with motor recovery were an increment in the affected and a decrement in the unaffected primary sensorimotor cortex (SMC) activities. In conclusion, it seems that cortical reorganization occurred in parallel with motor recovery in hemiparetic patients with cerebral infarct. © 2003 Lippincott Williams & Wilkins, Inc.