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The cortical substrate of visual extinction

Karnath, Hans-OttoCA; Himmelbach, Marc; Küker, Wilhelm1


The authors of the referenced article [1] note the following errors.

Page 440, left column, line 1: ‘n=3’ should read ‘n=4’.

On page 440, left column, paragraph 3 of ‘Results’, a reference was cited incorrectly. The second sentence should read ‘ …and our own previous results concerning the cortical site of lesions leading to spatial neglect [14]’.

On page 440, right column, paragraph 3 of the ‘Discussion’, two references were cited incorrectly. The second sentence should read ‘The activated clusters (54,−42,13; [19]; 56,−36,24 and 55,−53,4; [20] fit very accurately to the center of overlap in patients with extinction found in the present study.’

On page 440, right column, final paragraph of the ‘Discussion’, another reference was cited incorrectly. The fourth sentence should read ‘Lesions of the PPC do not even produce an extinction-like reaction time pattern [15]’.

NeuroReport. 14(8):1189, June 11th, 2003.


Neuroimaging studies investigated the attentional systems of the human brain revealing two networks, one for voluntary allocation of attention and another for stimulus-driven attentional processes. Whereas lesions of the latter system were supposed to lead to spatial neglect, we show that such lesions rather are typical for the occurrence of visual extinction. Extinction describes the inability of brain-damaged patients to detect a contralesional target in the presence of a competing ipsilesional stimulus. In a sample of consecutively admitted patients with right hemisphere stroke, we found dissociable cortical substrates for spatial neglect and visual extinction. There was a surprising congruency between the typical lesion site in patients with extinction and the activation clusters found in previous neuroimaging studies of healthy subjects. The results show that the temporo-parietal junction (TPJ), considered to be a crucial part of the stimulus-driven attentional network, is the neural substrate of visual extinction.

Departments of Cognitive Neurology

1Neuroradiology, University of Tübingen, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany

CACorresponding Author:

Received 2 November 2002; accepted 9 January 2002

© 2003 Lippincott Williams & Wilkins, Inc.