Ageing

Diet-induced hypercholesterolemia enhances brain Aβ accumulation in transgenic mice

Shie, Feng-Shiun^{1 2}; Jin, Lee-Way²; Cook, David G.³; Leverenz, James B.⁴; LeBoeuf, Renée C.^{4 5 CA}

¹Nutritional Sciences Interdisciplinary Program

²Department of Pathology, Box 353410, Raitt Hall, Room 305, University of Washington, Seattle, WA 98195, USA

³Department of Medicine and Pharmacology, Box 353410, Raitt Hall, Room 305, University of Washington, Seattle, WA 98195, USA

⁴Department of Neurology and Psychiatry and Behavioral Sciences, Box 353410, Raitt Hall, Room 305, University of Washington, Seattle, WA 98195, USA

⁵Department of Pathobiology, Box 353410, Raitt Hall, Room 305, University of Washington, Seattle, WA 98195, USA

^{CA, 5}Corresponding Author and Address: Pathobiology, Box 353410, Raitt Hall, Room 305, University of Washington, Seattle, WA 98195, USA

Received 4 January 2002 accepted 11 January 2002

Abstract