MOTOR SYSTEMSEffects of transcranial magnetic stimulation of the posterior parietal cortex on saccades and vergenceKapoula, Zoï1, CA; Isotalo, Elina1,2; Müri, René M.4; Bucci, Maria-Pia1; Rivaud-Péchoux, Sophie3Author Information 1LPPA, Collège de France, CNRS UMR 9950, 11, place Marcelin Berthelot, FR-75005 Paris, France; 2Department of ENT, Helsinki University Central Hospital, FIN-00290 Helsinki Finland; 3INSERM U 289, Salpêtrière Hospital, Paris, France; 4Department of Neurology, University of Bern, Switzerland CACorresponding Author Received 7 September 2001; accepted 17 October 2001 Neuroreport: December 21st, 2001 - Volume 12 - Issue 18 - p 4041-4046 Buy SDC Abstract Previous studies showed that transcranial magnetic stimulation (TMS) of the posterior parietal cortex (PPC) prolongs the latency of intentional saccades. We examined whether a similar effect exists for reflexive saccades and vergence. To elicit reflexive movements, a gap paradigm was used; lateral saccades and vergence along the median plane were interleaved. TMS was applied on the right PPC 80 ms after target onset. Blocks without TMS were performed and a control experiment with TMS over the primary motor cortex. The latter had no effect on the latency of any type of movements. In contrast, stimulation of the PPC increased the latency of both saccades and vergence, suggesting that the PPC is involved in the triggering of reflexive movements both in direction and in depth. © 2001 Lippincott Williams & Wilkins, Inc.