COGNITIVE NEUROSCIENCE AND NEUROPSYCHOLOGYBrain lateralization for mismatch response to across- and within-category change of vowelsKasai, Kiyoto1,2, CA; Yamada, Haruyasu3; Kamio, Satoru1; Nakagome, Kazuyuki4; Iwanami, Akira1; Fukuda, Masato5; Itoh, Kenji6; Koshida, Ichiro7; Yumoto, Masato8; Iramina, Keiji9; Kato, Nobumasa1; Ueno, Shoogo9Author Information Departments of 1Neuropsychiatry, 3Radiology, 6Cognitive and Speech Science, 8Laboratory Medicine, and 9Biomedical Engineering, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan; 2Clinical Neuroscience Division, Laboratory of Neuroscience, Department of Psychiatry, Boston VA Healthcare System, Brockton Division, and Harvard Medical School, 940 Belmont St., Brockton, MA 02301, USA; 4Department of Psychiatry, Showa University School of Medicine, Tokyo 142-8566; 5Department of Neuropsychiatry, Gunma University School of Medicine, Gunma 371-8511; 7Department of Information Technology, Tokyo Engineering University, Tokyo 192-8580, Japan CACorresponding Author Received 10 May 2001; accepted 30 May 2001 Neuroreport: August 8, 2001 - Volume 12 - Issue 11 - p 2467-2471 Buy Abstract Differences in hemispheric predominance between across- and within-category change perception of vowels were assessed using a whole-head magnetoencephalography. The magnetic mismatch responses (MMNm) to pure-tone and vowel within-category changes were significantly predominant in the right hemisphere; on the other hand, vowel across-category MMNm did not differ in power between hemispheres. The results suggest that both hemispheres are symmetrically activated in the preattentive across-category change perception of vowels, while the within-category change of a vowel is analyzed as the change in physical features of the stimuli, thus predominantly activating the right hemisphere. Thus, the relative contribution of the left auditory cortex in the preattentive speech processing may occur only at the level of perception of the vowel across-category change. © 2001 Lippincott Williams & Wilkins, Inc.