Chemical, SensesAxillary pheromones modulate pulsatile LH secretion in humansShinohara, KazuyukiCA; Morofushi, Masayo; Funabashi, Toshiya; Kimura, FukukoAuthor Information Department of Physiology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan CACorresponding Author Received 14 December 2000; accepted 16 January 2001 Neuroreport: April 17, 2001 - Volume 12 - Issue 5 - p 893-895 Buy Abstract We examined the effect of axillary compounds on pulsatile secretion of serum luteinizing hormone (LH). Axillary compounds were collected from donor women in the follicular phase (FP) and the ovulatory phase (OP) and were treated with isopropyl alcohol (IPA). The recipient was not exposed to either axillary compounds or IPA for the first 4 h and was exposed to FP or OP compounds, or to IPA, during the next 4 h. The frequency of the LH pulse was increased by FP compounds and was decreased by OP compounds, but the LH pulse frequency was not changed by IPA. Therefore, in humans, pheromones may play a role in the modulation of the timing of ovulation by changing the frequency of pulsatile LH secretion. © 2001 Lippincott Williams & Wilkins, Inc.