LEARNING AND MEMORYReversible lesions of the rhinal cortex produce delayed non-matching-to-sample deficits in ratsBarnes, Steven J.1,3; Floresco, Stan B.1; Kornecook, Tom J.2; Pinel, John P. J.1Author Information 1Department of Psychology, University of British Columbia, 2136 West Mall, Rm. 2509, Vancouver, B.C., V6T 1Z4 2Douglas Hospital Research Center, McGill University, Verdun, Quebec, Canada 3Corresponding Author: Steven J. Barnes Received 1 September 1999; accepted 26 November 1999 Acknowledgements: This research was supported by grants from the Natural Sciences and Engineering Research Council of Canada to J.P.J.P., Natural Sciences and Engineering Research Council of Canada Postgraduate Scholarships to S.J.B. and S.B.F. and a Medical Research Council of Canada Postgraduate Scholarship to T.J.K. The authors would like to thank Lucille Hoover for her technical assistance. NeuroReport: February 7, 2000 - Volume 11 - Issue 2 - p 351-354 Buy Abstract Rats with cannulae guides implanted in the rhinal cortex were tested on a delayed non-matching-to-sample task, following either lidocaine or sham microinfusions. Bilateral lidocaine microinfusions to the rhinal cortex produced significant delayed non-matching-to-sample deficits. These results are consistent with the putative role of the rhinal cortex in object recognition but because the deficits were not shown to be time dependent, non-mnemonic interpretations cannot be ruled out. These results also illustrate the utility of reversible lidocaine lesions in the study of the neuroanatomical basis of delayed non-matching-to-sample. © 2000 Lippincott Williams & Wilkins, Inc.