Vision, RetinaGABAB receptors in Müller cells of the bullfrog retinaZhang, Jun1; Yang, Xiong-Li1,2Author Information 1Shanghai Institute of Physiology and Key Laboratory of Neurobiology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China. 2Corresponding Author: Xiong-Li Yang ACKNOWLEDGEMENTS: We thank Dr Cheng Huang for kindly presenting GFAP antiserum, Dr Jiu-Lin Du for helpful discussion and assistance, Lai-Wen Fu, Tie-Feng Zhang and Hong-Yin Shan for skillful technical assistance. This work was supported by a grant from the National Natural Sciences Foundation of China, 39800041 and a grant from the Ministry of Science and Technology of China (Climbing Program). Received 12 April 1999; accepted 20 April 1999 NeuroReport: June 23rd, 1999 - Volume 10 - Issue 9 - p 1833-1836 Buy Abstract GABA is a major inhibitory neurotransmitter in the vertebrate retina. Using GABAB receptor-specific antibody combined with glial fibrillary acidic protein (GFAP) antiserum, we demonstrated that primary processes, vitreal endfeet and somata of virtually all Müller glial cells in the bullfrog retina prominently showed GABAB receptor immunoreactivity by light and electron microscopy. This study provides the first evidence that glial elements in the vertebrate retina express GABAB receptors. Such receptors on Müller cells may play an important role in retinal information processing through regulating the conductance of the inward-rectifying K+ channels. © 1999 Lippincott Williams & Wilkins, Inc.